Solgar Alpha Lipoic Acid 200 mg Vegetable Capsules - Food Supplement, Pack of 50 - Antioxidants - Vegan, Gluten Free

I found this product helpful. Best taken in the morning, either 30 minutes before a meal or 2 hours after. Avoid taking it at night as it may affect sleep.

If you know what you are doin, this can rly help you, if not pls read below: We have shown previously that the antioxidant alpha-lipoic acid (ALA) can stimulate glucose transport and can enhance the stimulation of this process by insulin in skeletal muscle from insulin-resistant obese Zucker rats. As insulin can also acutely activate general protein synthesis and inhibit net protein degradation in skeletal muscle, we hypothesized that ALA could directly affect protein turnover and also increase the effect of insulin on protein turnover in isolated skeletal muscle from developing obese Zucker rats. In epitrochlearis muscles isolated from obese Zucker rats, insulin (2 mU/ml) significantly (p < 0.05) increased in vitro protein synthesis (phenylalanine incorporation into protein) and decreased net protein degradation (tyrosine release), whereas a racemic mixture of ALA (2 mM) had no effect on either process. Interestingly, rates of protein synthesis in muscle from obese Zucker rats were substantially lower compared to those values observed in age-matched insulin-sensitive Wistar rats, whereas rates of protein degradation were comparable. Obese Zucker rats were also treated chronically with either vehicle or ALA (50 mg/kg/d for 10 d). Again, insulin significantly increased net protein synthesis and decreased net protein degradation in epitrochlearis muscles isolated from vehicle-treated obese Zucker rats; however, this stimulatory effect of insulin was not improved by prior in vivo ALA treatment. These results indicate that the previously described effect of the antioxidant ALA to increase insulin-stimulated glucose transport in skeletal muscle of obese, insulin-resistant rats does not apply to another important insulin-regulatable process, protein turnover. These findings imply that the cellular mode of action for ALA is restricted to signaling factors unique to the activation of glucose transport, and does not involve the pathway of stimulation of general protein synthesis and net protein degradation.

I took this supplement for a month and have now finished the bottle. It was recommended to me as a better alternative to berberine, so I decided to give it a try. I took it consistently, but to be honest I did not notice any difference. I didn’t feel that it helped with my blood sugar or with weight loss. Perhaps one month was not long enough, but based on my experience I didn’t see any clear benefits. One thing I do like is the quality. Like other Solgar supplements, it comes in a glass bottle, which I appreciate, and the product itself seems well made. However, I have stopped taking it because I didn’t notice any improvement

I am using these tablets after watching a video about neuropathy. This is just a top up. I think it is slightly better, but wouldn’t say it has cured the problem. Product came next day as ordered. Good service from seller.

It’s very good health product

A good supplement for your body , you gone see the difference after a day

The vitamin has expired. I cannot return it. a complete disappointment…today 3 feb 2024

take one - survive - feel the difference following day!

Genial!!

It was delivered in perfect condition. I've been using this alhpa lipoic acid for a while. My doctor recommended it. It has helped to lessen the sciatica pain. It's easy to swallow and has no taste.

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Ürün orijinal

this is the first i have been taking capsules around 20 days consistently , it gives me solid relax with reduced PAIN level and numbness you may go for it