

🐾 Elevate your dog’s digestion game—because they deserve the best!
Pan-tenex 10x Digestive Enzymes for Dogs delivers the highest potency porcine pancreatic enzymes to optimize digestion of fats, proteins, and carbohydrates. This acetone-free, low-odor powder is dosed per meal for precise, cost-effective use, supporting dogs with sensitive stomachs or conditions like EPI. Trusted by thousands, it improves stool quality, nutrient absorption, and overall vitality, making it a smart, affordable choice for large breeds.

| Brand | Pan-tenex |
| Customer Reviews | 4.6 out of 5 stars 781 Reviews |
| Dog Breed Size | Large |
| Flavor | Pork |
| Item Form | Powder |
| Item Weight | 8.8 Ounces |
| Manufacturer | AVF, LLC |
R**I
FANTASTIC AND NOT AS COSTLY
I have a 10 month old sweet beautiful black Lab who was recently diagnosed with Endocrine Pancreatic Insufficiency (EPI). She had diarrhea since I got her at the age of 4 months. It was a nightmare having such a big dog with diarrhea. Unfortunately it took a long time to get this diagnosed since she had anxiety and also had Giardia which was thought to be the cause. Once diagnosed with EPI the Vet prescribed Pancreatic enzymes which cost about $430 a month thru their pharmacy since she required a tsp with each meal 3x a day. They worked very good and stopped the diarrhea which was great. However, due to the cost I decided to look around for something cheaper….hopefully a generic brand. I came across this Pan-tenex. Since it had just about the same enzyme ingredients except for additional Vitamins A, D & E, I decided to give it a try. I figured I could give her the extra vitamins thru a puppy vitamin. Well to my surprise the consistency to her stool was even better with this cheaper brand and with auto ship is costing under $160 vs $430 with the prescription brand. I’m also giving her a multi puppy vitamin to supplement vitamin A, D & E which Pan-tenex doesn’t appear to list on the jar. These enzymes are life saving because without them the dog will literally starve to death since they aren’t processing and digesting the nutrients. I am giving her a low fiber kibble 3x a day so it is easier to digest mixed with the Pan-tenex and a little water….4% or less fiber which they list on the bag. Make sure you mix the kibble and powder well with a little water and wait 15 to 20 minutes for the enzymes to activate. If your dog has EPI try this brand of pancreatic enzymes. She doesn’t mind the powder mixed in.. Her weight is good and her coat is shiny. You will know in a day or so if it’s working by the consistency of the dogs stool. It’s the consistency of the stool that tells you if your dog is properly digesting its food and getting the proper nutrients. If it doesn’t work and the stool is soft you can always go back to the expensive brand and look further in the meantime. Try it you have nothing to lose!
T**Y
Noticeable Difference for Dogs with Sensitive Stomachs
Watching my dog feel good again after so many tummy issues makes this product worth every penny. I bought this to support my German Shepherd with EPI (exocrine pancreatic insufficiency), and the difference has been clear. I’ve tried a few other enzyme powders over the years, but this one seems more potent and better tolerated; it has less odor, a smoother consistency, and mixes easily into wet food without clumping. Within about a week, I noticed her stools firmed up, her appetite improved, and her coat looked healthier. She’s maintaining her weight well, and there’s no more stomach gurgling or grass-eating between meals. The powder itself smells a bit strong (which is normal for real enzymes), but it’s not offensive once blended with food. I appreciate that the company includes clear dosage guidance by weight; it makes it easy to adjust for larger breeds. A little goes a long way, and the 8.8-ounce container lasts longer than expected. For dogs with chronic digestive issues or EPI, this supplement has been a reliable, effective addition to their routine. I’ll definitely repurchase.
B**A
Pleased with Results
This works well! We have this in addition to tablets prescribed by the vet. Both work well for my dog, who was dx with EPI in December. This product is more affordable than the prescription tablets. My dog's stool is much more normal now. She has stopped losing weight too. The longer the enzymes sit in the moist food, the better it works for her.
A**N
Great Stuff
This stuff saved my dog’s life. She lost 20 pounds in 2 weeks. Vet said she was healthy just not at weight…EPI diagnosis by my wife’s research. After giving her these enzymes, she looked normal in a week.
N**S
Its been helping my pups EPI
Ive been buying meds for my dogs EPI in tablet form which requires me to use a pill crusher to break it down to powder form. My dogs vet suggested the powder form a while back. I should have listened which would have saved me a lot of money. So far with the first canister bought, my dog is now used to it. She did have some issues like upset stomach vomiting and stools issue. But very important to check with your vet and always read the directions and the right dose since this is powder form. Its not all the way powdery and I've tried using the pill crusher to see if I can get it more powdery, but it wasnt doing the job. Other than that, my dog is doing well.
S**C
Good Product
Dog has EPI and this was highly recommended. It worked well in the beginning but it’s starting to taper off. May need to increase her dosage though.
L**B
Resolved digestive problem
My dog developed a malabsorption issue that would’ve caused her death I’m sure. After many veterinary visits and an emergency trip to the veterinary hospital, she was still getting progressively worse. Last Christmas I thought would be her last—but I happened to find this product and took a chance on it. I’m not overstating the results when I say it saved my dog’s life. She started feeling better within 24 hours and within 2 weeks her body was very noticeably filling out. I moisten 1 cup of kibble per feeding with a little warm water then mix a half teaspoon of Pan-tenex in and let it sit at least15 minutes. With these enzymes her digestive issues have resolved and she’s at a healthy weight now. I’m so happy I can purchase this product though Amazon on a subscription basis so she will never be without it.
L**.
Great product
This was a life saver for our dog, after a severe case of pancreatitis, it helps her digestion and keeps her fed
C**A
My GSD was incredibly underweight when I adopted her from a rescue. They had told me she had EPI. I thought I would give this a try and it started working within a week. She no longer has diarrhea and gained weight right away. It is a tsp with each feeding and lasts about a month and a half.
S**E
Meilleur produit pour chien ayant IPE
L**D
They work! From a very sick puppy with pancreatitis 3 years ago my dog is healthy, happy and an athletic diva!
A**R
Thought my dog had IBD, tried this product. UNREAL his symptoms have all disappeared. What a life changer, he will continue on this product. Thank you
A**R
I had meds from the vet for a fortune.. meds from the US for a high price too. This product is by far the best price and actually the most effective in treating my dogs EPI.. life saver!
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