







❤️ Elevate your heart game with science-backed TMG!
Life Extension TMG delivers a pure, scientifically validated dose of trimethylglycine to support healthy homocysteine levels—a key marker of cardiovascular health. Available in vegetarian capsules or powder, this non-GMO, gluten-free formula is crafted in the USA to fit seamlessly into your longevity and wellness routine.










| ASIN | B00I509FZI |
| Age Range Description | Adult |
| Allergen Information | Gluten Free, Non-GMO |
| Best Sellers Rank | #6,632 in Health & Household ( See Top 100 in Health & Household ) #124 in Blended Vitamin & Mineral Supplements #789 in Sales & Deals |
| Brand | Life Extension |
| Brand Name | Life Extension |
| Color | Clear |
| Container Type | Bottle |
| Customer Reviews | 4.4 out of 5 stars 2,136 Reviews |
| Diet Type | Vegetarian |
| Dosage Form | Capsule |
| Flavor | Unflavored |
| Global Trade Identification Number | 00737870185963 |
| Item Dimensions | 2 x 2 x 3.75 inches |
| Item Form | Capsule |
| Item Nype Name | Trimethylglycine Supplement |
| Item Weight | 3.2 ounces |
| Manufacturer | Life Extension |
| Manufacturer Part Number | 01859 |
| Material Features | Vegetarian |
| Material Type Free | Gluten Free, Non-GMO |
| Model Name | TMG |
| Model Number | 01859 |
| Number of Items | 1 |
| Primary Supplement Type | Trimethylglycine (TMG) |
| Product Benefits | Encourages whole-body health, Helps inhibit inflammatory factors to encourage cardiovascular health, Helps maintain healthy mitochondrial function, Promotes healthy homocysteine levels already within normal range, Supports already-healthy blood pressure levels |
| Special Ingredients | Trimethylglycine (TMG) |
| Specific Uses For Product | Heart Health |
| Total Servings Per Container | 30.0 |
| UPC | 737870185963 |
| Unit Count | 60 Count |
O**A
Clean, Simple, and Effective
This Life Extension TMG is a solid, no‑nonsense supplement. The capsules are easy to take, the formula is clean, and it fits well into a daily routine. A reliable option if you want straightforward support without any unnecessary additives.
P**O
Essential Companion to NMN in My Longevity Stack
The primary reason for adding TMG when using NMN or NR is because they increase intracellular NAD⁺ levels which accelerates the activity of methyltransferase enzymes. This can create a significant demand for methyl groups and temporarily elevate homocysteine if methyl donors are insufficient. TMG serves as a methyl donor directly converting homocysteine back to methionine via the betaine-homocysteine methyltransferase pathway. Two capsules with breakfast provide exactly the 1–1.5 g range frequently cited in longevity-focused protocols. For anyone incorporating NMN, NR, or high-dose niacin into a longevity regimen, I consider TMG essential for maintaining methylation balance and minimizing potential homocysteine elevation. This particular TMG offering from Life Extension delivers reliable purity, potency, and value.
B**N
Lowered my BP
Life changing results for my blood pressure
K**C
Helps me absorb vitamins better.
The difference is amazing! I started taking this to help with better absorption of my vitamins. I notice a huge difference and I feel better since taking it. I feel my health is much better since taking this. I feel like I can finally feel the benefits of my B complex vitamins. I take two in the morning with my b complex vitamins (Thorne MethlGaurdPlus) on an empty stomach with no problem. No upset to my stomach. I’ve been taking for a few months now without any issues. Great price and quality. Easy enough to swallow. A must have if you have Issues with methylation that are common with gene mutation.
N**E
Great Product
TMG by Life Extension is the best. I tried the powdered capsule from another brand and hated it. Something about the liquid capsule form and the quality of the product makes me feel better throughout the day. I would highly recommend you give this one a try!
M**A
Good product but ongoing problem with leaky capsules
I bought this product about 6 times and the most recent bottles have had leaky capsules. The liquid gets all over the other pills, so I can't put them in my pill boxes. I am going to look for a replacement even though I really like this one.
J**L
Quality product, experiencing good effects
Appears to be good clean quality and transparent capsules where you can see the product. I took a methylation test a while back and discovered partial COMT varient issues. In taking these I notice a sustained energy throughout the day. Not sure if it's just a coincidence at this point but I will be continuing with this brand's tmg.
J**D
Great Product
Great quality and fast delivery.
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