







🦷 Elevate your smile game with science-backed, fluoride-free enamel care!
This dentist-formulated toothpaste harnesses 11% nano-hydroxyapatite, a NASA-developed mineral trusted in Japan for decades, to remineralize and strengthen enamel while reducing sensitivity. Its fluoride-free, vegan, and glycerin-free formula includes xylitol, aloe, and sea salt for comprehensive cavity protection and gum health. With a low RDA and neutral pH, it offers gentle yet effective daily oral care, delivering natural whitening and lasting value without harsh chemicals.























| ASIN | B0B8PFMGFW |
| Best Sellers Rank | #12,492 in Health & Household ( See Top 100 in Health & Household ) #222 in Toothpaste |
| Customer Reviews | 4.3 4.3 out of 5 stars (2,742) |
| Date First Available | January 5, 2023 |
| Manufacturer | Great Oral Health |
| Product Dimensions | 3.8 x 5.1 x 17.8 inches; 4.94 ounces |
R**M
Fluoride-Free for 5+ Years – Nano-Hydroxyapatite Toothpaste That Actually Works
Our family made the switch to fluoride-free toothpaste over 5 years ago after I began researching the long-term effects of fluoride. I had concerns, especially about daily exposure for children, and wanted a safer, more natural alternative. That’s when I discovered nano-hydroxyapatite (n-Ha) and we’ve never looked back. During my research, I learned that countries like Japan have used nano-hydroxyapatite for decades, instead of fluoride, to prevent cavities and rebuild enamel. Japan also does not fluoridate its water, yet still ranks among the top nations for dental health. Toothpastes like Apagard Premio are a great example of Japan’s success with n-Ha. This form of calcium, originally developed by NASA, binds to and fills in microscopic cracks in the enamel, reducing sensitivity and strengthening teeth over time. Since switching, we’ve experienced a big reduction in tooth sensitivity and visible improvements in enamel strength. This particular toothpaste has become my daily go-to, while I use Apagard Premio for natural whitening and Boca fluoride-free toothpaste for soothing my teeth on more sensitive days. To get the most benefit from nano-hydroxyapatite toothpaste, here’s how to use it: Brush as usual for at least 2 minutes Do not rinse immediately after brushing, just spit out the excess Let the residue sit on your teeth for as long as possible so the n-Ha can continue to remineralize the enamel Use twice daily for best results Pros: Fluoride-free and non-toxic Uses nano-hydroxyapatite (trusted in Japan for decades) Remineralizes enamel and reduces sensitivity Safe and gentle for adults and children Clean taste, non-foaming formula Cons: Less foaming than traditional toothpaste (but that’s intentional and actually better) Whitening is gentle and gradual, not instant If you're exploring a healthier alternative to fluoride, I highly recommend this toothpaste and nano-hydroxyapatite in general. It’s well-researched, used globally, and has made a huge difference in our family’s oral health.
W**�
No glycerin, great price, it works!
I looked high and low for a Hydroxyapatite toothpaste that did NOT contain glycerin, this is one of the very few (if not the only one) that is glycerin free, if you are wondering why, glycerin coats your teeth and can prevent re-mineralization which would defeat the purpose of this particular toothpaste. I am on my second tube, I wanted to use it for a while to make sure it worked, and it does. The toothpaste is a bit on the thinner side (compared to other toothpastes), which is fine, it does not affect it at all, it works fine, just be aware that when you squeeze some out, it will come out faster than you expect and might even run down the side of the toothbrush, I am frugal with it, I don't squeeze out a bunch of it so it's not a problem. I also "shake" the tube a bit before I open it, since it's thinner, I want to make sure all the ingredients are equally mixed in the tube before I squeeze it out, I don't know for a fact that it does or does not separate, it's just something I do for my own peace of mind. I brush my teeth with this toothpaste and spit it out but I don't rinse, I allow the residual toothpaste to remain in my mouth and on my teeth to get the most benefit from it. I noticed that within a few days, my teeth were less sensitive, I don't have a major problem with sensitivity but I did notice the difference. I feel like this gets my teeth and mouth very clean. I like the ingredients, the flavor is not like other toothpaste, it has more natural ingredients so it doesn't have that blasting, knock your head off mint flavor like so many other toothpastes have, this is more subtle, pleasant. I also noticed that my bottom teeth seem tighter, if I use a different toothpaste for a few days, I feel like my bottom front teeth move a little, not major movement, but it's there. When I use this toothpaste regularly, daily, it makes my teeth feel more tight. Bottom line, I will continue using this.
K**H
A Toothpaste That Tries—And Mostly Succeeds
I recently used a whole tube of this product which lasted almost about 3 1/2 months at two uses per day. I liked the orange taste and the mouth feel it has, which is a little foamy, but not too much. My teeth handled it well and did not have sensitivity or toxicity reactions to it. Overall, I'd say it felt healthy for my mouth. For those of you who don't know, nano‑hydroxyapatite is an ultra‑small version of the natural mineral that makes up most of your tooth enamel, and toothpaste uses it because those tiny particles can slip into microscopic cracks and weak spots in your enamel. By filling those little gaps, it helps smooth the tooth surface, reduce sensitivity, and strengthen the outer layer of your teeth in a way that mimics your body’s own enamel. The instructions say that for best results, after spitting it out, allow a minute or two before rinsing your mouth. I followed that, but it was a little annoying and threw off my routine a little. Not the end of the world, just sayin'. Another con was that the toothpaste dries out on the nozzle over time and makes the lid hard to close without cleaning it off. Again, not the end of the world, but just a small bother. Another nano hydroxyapatite toothpaste I have doesn't do that at all and I think it has to do with the aperture design and consistency of the toothpaste. I was also using an oil pulling product for the last month, so I don't know how much difference the toothpaste made in the shade improvement of my teeth vs. what the oil pulling did, but there is an improvement. I'm sure it contributed.
N**Y
I don't love the taste of it, I'll buy the mint one next time. I do like the toothpaste though, .
U**1
ممتاز لكن نكهة النعناع قوية جداً للي ما يتحملها
B**D
I’ve been using the Pro-Mineralizer Toothpaste in Wintermint for a few months now, and it’s truly become a staple in my oral care routine. The wintermint flavor is refreshing but not too overpowering, leaving my mouth feeling fresh and clean. What I love most is that it’s fluoride-free and uses Nano Hydroxyapatite, which supports enamel restoration in a more natural way. Beyond the flavor and the main ingredient, the added ingredients like aloe vera and sea salt have been fantastic for my overall oral health. Aloe vera is known for its soothing properties, and I feel it’s really helped keep my gums in good condition, while the sea salt helps with gentle cleaning. Xylitol is another great addition, as it’s known to help fight bacteria and reduce the risk of cavities. These natural ingredients make me feel confident about what I’m putting in my mouth every day. After several months of use, my teeth are less sensitive, and they feel smoother and stronger. While the price is a bit higher than regular toothpaste, the benefits I’ve experienced make it well worth it. If you’re looking for a natural toothpaste that effectively supports oral health with high-quality ingredients, I highly recommend giving this one a try!
S**L
Fantastic toothpaste. It really relief tooth sensitivity. It doesn’t taste horrible like fluoride toothpaste. I never get back to rubbish fluoride
P**L
Kam aufgebläht an, aber ansonsten war alles gut.
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